Colorectal cancers account for 783,000 new cases and cause 437,000 deaths per year across the
world. Diagnosis in the early stages improves survival rates. Up to now, these cancers are
mostly diagnosed only at later stages of the disease's course through histoimmune staining
and molecular biology processes on the tissues biopsied from the gastrointestinal system
under invasive diagnostic procedures of colonoscopy.
Oral fluid presents a large protein complexity and has been recently used as a diagnostic
biofluid for oral, as well as systematic diseases. Using oral fluid as a bio-marker for the
colorectal cancer can be advantageous as it contains gastrointestinal fluids, in addition to
bacteria and bacteria lysate, which can also serve as a bio-markers' source for colorectal
cancers. Proteomic technologies provide the tools needed to discover and identify
disease-associated biomarkers.
The aim of the present study is to identify salivary bio-markers in patients suffering from
colorectal cancers.
Sep 30,2012
All
18 Years
N/A
18 Years
N/A
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