PulMiCC
Patients who have been treated successfully for bowel cancer (colorectal cancer) sometimes go
on to develop nodules of disease in another part of the body. If this disease is found to be
related to the original cancer it is called a metastasis. Some patients develop one or more
metastases particularly in the lungs or the liver.
There is a growing trend to remove lung metastases with an operation, in the belief that this
will help patients live longer, however there have not been any scientific studies to prove
this. There is also very little published information about the side effects of this surgery
and how it affects subsequent daily living. This is a feasibility study to determine whether
it will be possible to conduct a large randomised controlled trial investigating the value of
pulmonary metastasectomy (surgery to remove lung metastases) in patients who have been
successfully treated for colorectal cancer. There is a two stage consent and randomisation
process. Firstly, patients will be invited to consent to having a full range of
investigations to assess their suitability for surgery. If found to be suitable, they will
then be invited to consent to randomisation between active monitoring of their disease or
active monitoring with pulmonary metastasectomy. Patients will be followed up regularly for 5
years to assess their disease status and to measure their quality of life and lung function.
Apr 30,2010
All
16 Years
N/A
16 Years
N/A
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