Drug Database for Digestive Cancers

We often receive the question: ‘which drugs or pharmaceutical treatments (chemotherapy, immunotherapy) are available for patients with digestive cancers? What drugs are available for bowel cancer or colorectal cancer, for gastric cancer, for oesophageal cancer, for liver cancer, pancreatic cancer or for rare digestive cancers?’ This database can give you an indication and answers.

It’s simple to use the database:

  1. Select which type of digestive cancer you want information about via: ‘Type of Cancer’
  2. Select whether you are looking for treatments that are still ‘In Development’ or ‘Approved for Market Access’*

*In Development means that these compounds are currently being researched in Phase II (small group of patients) or Phase III (large group of patients). This information is derived from international analyses and from the individual companies involved.

Approved for Market Access means that the European Medicines Agency (EMA) has approved this drug for marketing in the European Union. It does not necessarily mean that this treatment is already available in your country.

Please note the following about the database:

  • It is possible that one molecule is already approved for one indication (for instance colorectal cancer) but not yet approved for another type of cancer (for instance gastric cancer).
  • In the list you can also see which companies are the ‘marketing authorisation holder’ for the treatment or the developer of the compound, and in which country their headquarters are located.
  • It is only indicative and several of the drugs mentioned are indicated for small subpopulations of the cancer mentioned. Please discuss these options with your treating medical team if you want more information on whether it is suitable for you or available.
  • ‘Country’ in the table identifies the country of origin of the company developing or selling the medicine
  • It is updated once a year, but please let us know if more urgent changes need to be made.
DrugCompanyCountry
Masitinib (AB-1010)AB ScienceFrance gastric cancer, colorectal cancer
Capecitabine (generic)Accord HealthcareUnited Kingdom gastric cancer, colorectal cancer
Lutathera (lutetium Lu 177 dotatate) (NET)Advanced Accelerator Applications (Novartis)United States rare cancer
IvosidenibAgios PharmaceuticalsUnited States liver cancer
Trastuzumab biosimilarAllerganIreland gastric cancer
Vectibix (Panitumumab)AmgenUnited States colorectal cancer
Kanjinti (Trastuzumab biosimilar)AmgenUnited States gastric cancer
Mvasi (Bevacizumab)AmgenUnited States colorectal cancer
AMG 510 (II)AmgenUnited States colorectal cancer
Crenolanib (GIST) (III)AROG PharmaceuticalsUnited States gastric cancer
Derazantinib (ARQ 087) (III)ArQuleUnited States liver cancer
Encorafenib (BRAF inhibitor)Array BiopharmaceuticalsUnited States colorectal cancer
IpatasertibArray BiopharmaceuticalsUnited States colorectal cancer
Varlitinib (II/III)Aslan PharmaceuticalsSingapore biliary tract cancer
IMAB362 (zolbetuximab)AstellasJapan oesophageal cancer, gastric cancer
Lynparza POLOAstraZenecaUnited Kingdom/Sweden pancreatic cancer
Imfinzi (Durvalumab )AstraZenecaUnited Kingdom/Sweden oesophageal cancer, gastric cancer, colorectal cancer, pancreatic cancer
Lynparza (II)AstraZenecaUnited Kingdom/Sweden gastric cancer
Imfinzi (Durvalumab) (II)AstraZenecaUnited Kingdom/Sweden oesophageal cancer, gastric cancer, liver cancer, biliary tract cancer
Tremelimumab (II)AstraZenecaUnited Kingdom/Sweden oesophageal cancer, gastric cancer, colorectal cancer
Stivarga (Regorafenib)BayerGermany gastric cancer, liver cancer, biliary tract cancer, rare cancer
Nexavar(Sorafenib)BayerGermany liver cancer
Vitrakvi (Larotrectinib) (NTRK)BayerGermany oesophageal cancer, gastric cancer, colorectal cancer, liver cancer, biliary tract cancer, rare cancer
SelitrectinibBayerGermany oesophageal cancer, gastric cancer, colorectal cancer, pancreatic cancer, liver cancer, biliary tract cancer, rare cancer
Stivarga (Regorafenib) (II)BayerGermany biliary tract cancer
Tislelizumab (BGB-A317) (III)BeiGeneChina liver cancer
Opdivo (Nivolumab)BMSUnited States colorectal cancer
TaxolBMSUnited States pancreatic cancer
Yervoy (Ipilimumab)BMSUnited States colorectal cancer
Opdivo (Nivolumab)BMSUnited States oesophageal cancer, gastric cancer, colorectal cancer
BMS-986183 (II)BMSUnited States liver cancer
Linrodostat (BMS-986205) (II)BMSUnited States gastric cancer
Relatlimab (II)BMSUnited States gastric cancer, colorectal cancer
Yervoy (Ipilumab) (III)BMSUnited States oesophageal cancer, gastric cancer, colorectal cancer
Bevacizumab Biosimilar (BI 695502)Boehringer IngelheimGermany colorectal cancer
Napabucasin (BBI-608)Boston BiomedicalUnited States colorectal cancer
Napabucasin (II)Boston BiomedicalUnited States gastric cancer
Amcasertib (BBI503)Boston BiomedicalUnited States liver cancer
Namodenoson (CF102)Can-Fite BioPharmaIsrael liver cancer
Polyclonal antibody stimulator (III)Cancer AdvancesUnited States gastric cancer
Onvansertib (II)Cardiff OncologyUnited States colorectal cancer
ENMD-2076 (II)CASI PharmaceuticalsChina liver cancer
AbraxaneCelgeneUnited States gastric cancer, pancreatic cancer
Tislelizumab (BGB-A317)CelgeneUnited States oesophageal cancer
Herzuma (trastuzumab biosimilar)CelltrionKorea gastric cancer
ThermoDox (doxorubicin liposomal) (III)CelsionUnited States liver cancer
Trastuzumab Deruxtecan (DS-8201) (II)Daiichi SankyoJapan gastric cancer, colorectal cancer
DCC-2618 (GIST - III)Deciphera PharmaceuticalsUnited States gastric cancer
eFT508 (II)eFFECTOR TherapeuticsUnited States liver cancer
Lenvima (Lenvatinib)EisaiJapan liver cancer
Rivoceranib (III)Elevar TherapeuticsKorea gastric cancer
Andecaliximab (II)GileadUnited States gastric cancer
bintrafusp alfaGSKUnited Kingdom biliary tract cancer
INCB54828 (II)InCyteUnited States liver cancer
INCB62079 (II)InCyteUnited States liver cancer
SomatulineIpsenFrance rare cancer
Cabozantinib (Cabometyx)IpsenFrance liver cancer
eFT508 (MKNK1/MKNK2 protein inhibitor)Isofol Medical ABSweden colorectal cancer
Modufolin (arfolitixorin) (III)Isofol Medical ABSweden colorectal cancer
ErdafinitibJanssenUnited States oesophageal cancer, gastric cancer
Imbruvica (ibrutinib) (III)JanssenUnited States pancreatic cancer
Famitinib (III)Jiangsu HengRui MedicineChina colorectal cancer
Ecansya (generic Capecitabine)KrkaSlovenia gastric cancer, colorectal cancer
DKN-01 (anti-DKK1 mAb) (II)Leap TherapeuticsUnited States biliary tract cancer
Cyramza (Ramucirumab)LillyUnited States oesophageal cancer, gastric cancer, colorectal cancer, liver cancer
GemzarLillyUnited States pancreatic cancer
ErbituxLillyUnited States colorectal cancer
Phase IIILillyUnited States pancreatic cancer
galunisertib (II)LillyUnited States liver cancer
merestinib (II)LillyUnited States biliary tract cancer
Vinorelbine Tartrate (II)LillyUnited States colorectal cancer
Capecitabine (generic)MedacGermany gastric cancer, colorectal cancer
Erbitux (Cetuximab)MerckGermany colorectal cancer
Peposertib (M3814, DNA-PK inhibitor) (Phase II)MerckGermany colorectal cancer
Bintrafusp Alfa (II and II/III)MerckGermany biliary tract cancer
Keytruda Phase IIIMSDUnited States oesophageal cancer, gastric cancer, colorectal cancer, liver cancer, biliary tract cancer
Keytruda Phase II (dMMR)MSDUnited States rare cancer
Lynparza phase IIIMSDUnited States pancreatic cancer
Ogivri (Trastuzumab biosimilar)Mylan/UpjohnUnited States gastric cancer
NC-6004 (II)NanoCarrierJapan liver cancer
Teysuno (Tegafur/Gimeracil/Oteraci)Nordic GroupFrance gastric cancer
AfinitorNovartisSwitzerland gastric cancer, pancreatic cancer
GleevecNovartisSwitzerland rare cancer
Capmatinib (INC280) (II) FGF401 (II)NovartisSwitzerland liver cancer
VPM087 (1L) (II)NovartisSwitzerland colorectal cancer
Tafinlar (Dabrafenib)NovartisSwitzerland rare cancer
Mekinist (Trametinib)NovartisSwitzerland rare cancer
Ellence (Epirubicin)PfizerUnited States gastric cancer
Camptosar (Irinotecan)PfizerUnited States gastric cancer, colorectal cancer
SutentPfizerUnited States rare cancer
Trazimera (Trastuzumab biosimilar)PfizerUnited States oesophageal cancer, gastric cancer
Zirabev (Bevacizumab)PfizerUnited States colorectal cancer
PM184 (II)PharmaMarSpain colorectal cancer
Binimetinib (MEK162)Pierre FabreFrance colorectal cancer
ensituximabPrecision BiologicsUnited States colorectal cancer
Infigratinib (BGJ398)QED TherapeuticsUnited States liver cancer
ABC294640 (Yeliva®)Redhill BioPharmaUnited States liver cancer
Herceptin® (Trastuzumab)RocheSwitzerland oesophageal cancer, gastric cancer
Avastin® (Bevacizumab)RocheSwitzerland colorectal cancer
Tarceva® (Erlotinib)RocheSwitzerland pancreatic cancer
Xeloda® (Capecitabine)RocheSwitzerland colorectal cancer
Tecentriq® (Atezolizumab)RocheSwitzerland colorectal cancer
Tecentriq® (Atezolizumab) (Ib/II)RocheSwitzerland oesophageal cancer, gastric cancer, pancreatic cancer
Tecentriq® (Atezolizumab) (III)RocheSwitzerland liver cancer
Tiragolumab (Ib/II)RocheSwitzerland oesophageal cancer, pancreatic cancer
Cotellic® (Cobimetinib) (Ib/II)RocheSwitzerland gastric cancer, pancreatic cancer
Cotellic® (Cobimetinib)RocheSwitzerland colorectal cancer
Avastin® (Bevacizumab) (I)RocheSwitzerland colorectal cancer
Avastin® (Bevacizumab) (Ib/II)RocheSwitzerland pancreatic cancer
Avastin® (Bevacizumab) (III)RocheSwitzerland liver cancer
Cibisatamab (I)RocheSwitzerland colorectal cancer
Selicrelumab (Ib/II)RocheSwitzerland pancreatic cancer
RO6874281 (Ib/II)RocheSwitzerland pancreatic cancer
Ontruzant (Trastuzumab biosimilar)Samsung BioepisKorea gastric cancer
5- Fluorouracil (generic)SandozSwitzerland gastric cancer, colorectal cancer
Capecitabine (generic)SandozSwitzerland gastric cancer, colorectal cancer
Docetaxel (generic)SandozSwitzerland gastric cancer
Oxaliplatin (generic)SandozSwitzerland colorectal cancer
Caclium Folinate (generic)SandozSwitzerland colorectal cancer
Irinotecan (generic)SandozSwitzerland colorectal cancer
Gemcitabine (generic)SandozSwitzerland pancreatic cancer
Trastuzumab biosimilarSandozSwitzerland gastric cancer
Taxotere (docetaxel)SanofiFrance oesophageal cancer, gastric cancer
Eloxatin (folfox)SanofiFrance colorectal cancer
Zaltrap (Ziv-Aflibercept)SanofiFrance colorectal cancer
LonsurfServierFrance colorectal cancer, pancreatic cancer
Lonsurf (Tipiracil/Trifluridine) (III)ServierFrance gastric cancer
OnivydeServierFrance colorectal cancer
Ph II & Onivyde (PhIII)ServierFrance pancreatic cancer, rare cancer
Lonsurf (1L)ServierFrance gastric cancer, colorectal cancer
Pexastimogene Devacirepvec (Pexa-Vec) (III)SillaJen BiotherapeuticsKorea liver cancer
Donafenib (III)Suzhou Zelgen Biopharmaceuticals CoChina colorectal cancer
Entinostat (II)Syndax PharmaceuticalsUnited States colorectal cancer
CMAB009 (III)Taizhou Mabtech PharmaceuticalChina colorectal cancer
Tirapazamine (TPZ) (II)TeclisonUnited States/Taiwan liver cancer
Capecitabine (generic)TevaIsrael gastric cancer, colorectal cancer
TRC-105 (II)TRACON PharmaceuticalsUnited States liver cancer

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